Plague Inc is a mobile game ported to console, and the real differences are as opposed to being free like it is on mobile where you can pay to unlock things, on the console you buy it and earn unlockables by playing. Aside from that and controller changes, it is the same game. You name your virus or fungus or whatever you design, plant it somewhere, choose how it evolves and spreads and try to kill everyone on earth.
While that is it and is just what the game is it is actually quite fun and hard to master. The scientist will try to find cures people will take better care of themselves as it spreads and countries will close their borders as it spreads. It is a fun little game I suggest you pick up on a sale as it isn’t really worth more than $5 or so. Best wishes and may the gaming gods bring you glory.